Catalog Biomaterials 2021

Biomaterials Product catalog 2021 | 13 LifeCell™ – over 25 years of experience For over two decades LifeCell™ has been developing innovative products for a wide range of applications. With over 2.5 million grafts to date, 25 years of experience in tissue processing and an ongoing commitment to innovation, LifeCell™ has joined forces with BioHorizons and Camlog to bring NovoMatrix™, the next generation soft-tissue augmentation material to dentistry. 2000 BioHorizons begins distribution of AlloDerm™ RTM for dentistry (U.S.) 2005 AlloDerm™ RTM for guided bone regeneration (U.S.) 2019 NovoMatrix™ Reconstructive Tissue Matrix for applications in dentistry (EU)* 1986 Foundation of the LifeCell™ Corporation * NovoMatrix™ is cleared for sale in the European Union. Success factor processing methods Tissue selection Manufactured from targeted porcine tissue for desired mechanical and handling properties. Dermis isolation Non-chemical based method that removes all non-dermal tissue retaining the structural integrity of the matrix. Microbial neutralization Proprietary process removes 99.9 % of the pathogens, enabling a more gentle preparation process. Decellularization & enzyme treatment Maintains the natural collagen structure while extracting the porcine alpha-gal antigen, as well as the cell and DNA components to minimize the xenogenic immune response. Matrix preservation The proprietary preparation process stabilizes the key matrix proteins as well as protecting the integrity of the acellular dermal matrix, thus providing a platform for tissue regeneration. Sterilization Optimized steriliza- tion process to preserve the natural tissue structure, thus retaining the regenerative properties of the acellular dermal matrix. Regeneration An intact acellular dermal matrix derived from porcine tissue that retains the biochemical components that support a positive immunological response and regeneration [17, 21, 22]. Histological structure of NovoMatrix™ 100 µm Histological structure of human dermis 100 µm Further information, videos and clinical case studies at www.biohorizonscamlog.com/novomatrix

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